J Dent. Pak Oral Dent J. However, they also suggested further comparative evaluations of two dentifrices with large sample sizes as limited scientific evidence was found in previous studies [16]. . YYYY Colgate-Palmolive Company. The sensitive toothpaste remineralises tooth enamel for more resistance against acid attacks. Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief . It improves gum health and helps reduce factors that contribute to gum recession, a leading cause of tooth sensitivity. Bakri MM, Hossain MZ, Razak FA, Saqina ZH, Misroni AA, Ab-Murat N, et al. Indian J Dent Sci. PubMed J Dent Probl Solut. This toothpaste prevents sensitivity coming back by building a protective barrier that acts like . Our study included an Asian population, and most of the published literature was associated with the Caucasian population. Colgate SENSITIVE Instant(Pro) Relief Enamel Repair Toothpaste 75ml (Pck 4,6,12) 15.99 to 39.99. The impact of FCPS, Pro-argin, and strontium acetate-based treatments of DH on the oral health-related quality of life together with the difference in the effectiveness of treatments were assessed individually rather than in groups in the current six-week trial. Terms and Conditions, 1. 1997;24(11):80813. 2017;9(4):e503. 2013;41(2):18794. [32] reported statistically significant improvement in mechanical stimulated DH with Pro-argin immediately after topical application relative to 8% strontium Acetate in 2016. Frequency of dentin hypersensitivity: a cross-sectional study. Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. J Dent. (Table 1) (Fig. CONSORT flow chart. Matranga D, Matera F, Pizzo G. Evaluating the statistical methodology of randomized trials on dentin hypersensitivity management. Colgate Sensitive Pro Relief Multi Protection, offering all of the above benefits in one convenient formula. Participants were recalled at interim efficacy intervals of three days, two weeks, four weeks, and six weeks for assessment of sustained relief. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial, https://doi.org/10.1186/s12903-021-01864-x, https://clinicaltrials.gov/ct2/show/NCT04249336, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. Wilcoxon Signed-Rank Test was used to compute mean scores relative to baseline at each time point. These participants were randomized equally by the principal investigator into four entitled treatment arms using computer-generated random sequence numbers, and treatments were allocated randomly using sequentially numbered, opaque, sealed, and stapled envelopes (SNOSE). 2018;2018:110. Baseline scores were recorded to measure the intensity of pain due to DH on SCASS with scores2 [22] against air blast stimulus with a triple syringe of the dental unit and on a linear VAS of 10cm length with scores4cm [23], against mechanical stimulus with a dental probe and water jet stimulus with a triple syringe. Bae J-H, Kim Y-K, Myung S-K. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta-analysis. A meta-analysis by Matranga et al. who examined FCPS and Pro-argin formulations in 2018. Saba Arshad. Compared to stannous fluoride/sodium fluoride and novamin/sodium fluoride. Therefore, the current study outcomes were analysed by parametric and non-parametric statistical tests after assessing the normal distribution of data and equality of variances with Shapiro Wilk statistics. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. By using this website, you agree to our The prime focus of treatment nowadays is based on the exploration of novel materials to remineralise the exposed tubular endings and mimic and restore the structure of the dentin [11]. Colgate Sensitive Pro-Relief Multi Protection Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily Register now and gain access to: 8 hours ECPD Product samples Patient materials Register here * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. was used for statistical analysis. The benefits are backed by over a decade of clinical research, summarized as follows. Desensitizing toothpastes for dentin hypersensitivity: a network meta-analysis. (US). All rights reserved. 3rd edition, Public Health England 2014. If the enamel is too thin, has tiny tubules that reveal the underlying dentin, or is worn down in some places. Explore the videos and articles found on this page to assist in better oral care. When you recommend Colgate Sensitive Pro Relief, you can help your dentin hypersensitivity patients to enjoy a pain-free life, confident in the knowledge that youre providing a highly effective, evidence-based solution. Hines D, Rinaudi L, Xu S, Lavender S, Pilch S: The Use of Confocal Laser Scanning Microscopy and a Novel Imaging Program for Quantifying Dentine Tubule Occlusion. Ingredients *Calcium carbonate *Water A randomised, controlled, triple-blinded clinical trial was conducted with 140 participants clinically diagnosed with DH and equally randomized into four groups with parallel treatment assignment of FCPS, Pro-Argin, 8% strontium acetate, and sodium fluoride-based OTC dentifrices, and tested for DH with air blast, mechanical, and water jet stimuli on SCHIFF cold air sensitivity scale (SCASS) and visual analogue scale (VAS) at interim efficacy intervals of one minute, three days, two, four, and six weeks, subsequently. Pro-argin resulted in the immediate treatment response and statistically significant (p<0.001) clinical reduction in DH than FCPS in the present study, as shown in Table 3. These fluorapatite crystals were less susceptible to acidic dissolution than hydroxyapatite crystals and thus were more desirable [13]. Fordeler Colgate SENSITIVE INSTANT Relief tannkrem er klinisk dokumentert virke i lpet av sekunder samtidig som den beskytter tannen mot at smerten skal komme tilbake. The arginine, calcium carbonate and phosphate plug created by Colgate Sensitive Pro Relief remains intact with ongoing use, even when exposed to acid challenges. Was this answer helpful? It was measured by assaying change in SCASS scores of pains with Pro-argin and 8% strontium acetate after one minute of topical application on the sensitive teeth. Douglas-de-Oliveira DW, Vitor GP, Silveira JO, Martins CC, Costa FO, Cota LOM. 2009; 20 (Spec Iss): 1722. I am interested to hear you guys opinion and thought about it. Grnberg C, Bauer F, Crispin A, Jakob M, Hickel R, Draenert ME. Colgate Sensitive Pro-relief Instant Relief. Colgate Sensitive Pro Relief was compared to a leading brand of desensitizing toothpaste containing stannous fluoride in a laboratory study, with confocal laser scanning microscopy and a novel imaging program used to qualify dentinal tubule occlusion. Kp nu. Builds a protective barrier that acts like . A total of 140 met the eligibility criteria with at least two sensitive teeth anterior to molars due to erosions or abrasions with or without an associated gingival recession. The Sensitive Pro-Relief Multi-Protection toothpaste by Colgate thoroughly cleans your teeth, while providing you with relief from sensitive tooth pain. Colgate Sensitive Pro-Relief Whitening Toothpaste provides clinically proven instant and lasting relief for sensitive teeth. According to Holland's guidelines of conducting a trial for managing DH, two diagnostic tools are sufficient for quantitative assessment of the clinical efficacy of desensitisers. 2017;71:18. The Pro-Argin technology repairs sensitive areas of the teeth for instant* and long-lasting sensitivity pain relief. Therefore, in the current study, we used a dental explorer and the air blast and water jet stimuli from the triple syringe of the dental unit for testing DH to control the subjective variations in treatment response. Comparing the efficacy in reducing dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a commercial sensitive toothpaste containing 2% potassium ion: an eight-week clinical study on Canadian adults. Am J Dent. In addition, one-Way ANOVA with Post Hoc Tukey for pair-wise comparison was used to compare treatment groups computing percent change from baseline with formula (post-application mean scores-baseline mean scores/baseline mean scores). Besides, these findings of the current study could be related to previously conducted clinical trials indicating the better clinical effectiveness of Pro-argin than strontium acetate against air-blast and tactile stimulus after three days and one week of application [30, 31]. For children 6-12 years of age, once a week or less frequently. It effectively occludes open dentine tubuli instantly* and builds a strong calcium-rich layer that ensures long-lasting relief from the pain of sensitivity.1,2 The protective layer remains strong even after exposure to acid attacks.3, of respondents confirmed reduced dentine hypersensitivity with Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste6,, of respondents were happy with their dentists recommending Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste6,, of respondents noticed long-lasting and instant* relief when brushing with Colgate SENSITIVE INSTANT Relief toothpaste7,, Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief. 2019;40(10):6537 (quiz 8). Zang P, Shaw D. A randomized clinical study to evaluate the efficacy of an 8%(w/w) strontium acetate dentifrice in providing relief from dentinal hypersensitivity. However, FCPS formulation showed 1% more improvement than Pro-argin and 7% more than strontium acetate-based dentifrices. Purchased in August 2019 at Coles for $5. [12] suggested a novel BAG component of fluoro-calcium phospho-silicate (FCPS)-containing OTC dentifrice, with the potential of fluorapatite-like crystals formation in dentin in 2017. After six weeks, Pro-argin-based dentifrices showed greater clinical efficacy with mean scores (2.151.92) than other treatment arms for mechanical stimulated DH. Ayad F, Ayad N, Zhang YP, DeVizio W, Cummins D, Mateo LR. Colgate Sensitive Pro-Relief (Toothpaste): 1.9 out of 5 stars from 91 genuine reviews on Australia's largest opinion site ProductReview.com.au. With regular use, it creates a long-lasting protective barrier that acts as a seal against sensitivity. A meta-analysis by Grnberg et al. For lsting relief, apply to a gentle toothbrush making sure to brush all . Table 2 presents descriptive statistics of the primary analysis population as the primary statistical analysis was performed for 47 males and 81 females of age ranging from 18 to 50years with a mean age of 34.18.9. The main etiological factors are abrasion and erosion that may or may not be associated with gingival recession in DH. We observed the varying treatment response at different efficacy intervals that could be due to the varying degree of patient's response to pain-provoking stimuli in DH. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. J Clin Dent. Paired sample T-test was used to compute mean scores to observe change relative to baseline at each time point. 1 Nathoo et al. The statistically significant change in mean scores of DH was observed with FCPS with p<0.05 relative to baseline for sustained relief from DH at follow-ups on day 3, week 2, week 4, and week 6, using clinical parameters of SCASS and VAS. A head-to-head comparative evaluation of these most effective bioactive agents, such as arginine and BAG-based desensitisers, was suggested by Martins et al. Hence, the current study outcomes, along with previously published findings, corroborate the in vitro findings of obliteration of dentinal tubules with strontium acetate impeding painful fluid movement in dentine [29]. [28] reporting the immediate effect of 8% strontium acetate in alleviating clinical symptoms of DH with clinically and statistically significant (<0.001) measures relative to baseline [26]. Colgate* Sensitive Pro-Relief TM/MC Toothpaste with Pro-Argin TM/MC Technology is the first toothpaste that is clinically proven to provide instant & lasting relief from dentin hypersensitivity. Clinically proven amino acid formula with Pro-Argin technology to provide sensitivity relief. Helps restore natural whiteness of teeth. More robust trials with a large number of participants are recommended for furtherassessing the impact of DH on the oral health-related quality of life and the difference in the effectiveness of treatments. Colgate Sensitive Pro-Relief efektywnie i szybko znosi nadwraliwo zbw, zamyka kanaliki zbinowe w ktrych s zakoczenia nerww, dziki czemu blokuje bl. The maximum sampling time was 15min. Friedman Test was used to observe post-application change in treatment responses within the group for 6weeks. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Plus it has the freshness you trust from Colgate! Docimo R et al. Thank you for your feedback. The comparative evaluation was done for the clinical efficacy of Pro-argin and 8% strontium acetate, and a statistically significant (p>0.05) difference was not found between these two formulations in the current study. J Clin Periodontol. * For instant relief apply to the sensitive tooth with a figure tip and gently massage for one minute. The effectiveness of Colgate SENSITIVE INSTANT Relief toothpaste is built on its Pro-Argin technology with arginine and calcium from calcium carbonate. There was a significant (p<0.001) reduction of 45.7% with Pro-argin, 37.6% with 8% strontium acetate, 18.1% with FCPS, and 15.2% with NaF-based dentifrices relative to baseline on SCASS after one-minute application on sensitive teeth. These findings were similar to a previous study conducted by Schiff et al. These findings were similar to a previous study conducted by Schiff et al. Pro-Argin technology provides instant* and long-lasting, Oral Care Products | Colgate Professional. Statistical Package for the Social Sciences software v.21.0. J Dent Res. Free postage. J Clin Dent. Colgate Sensitive Pro-Relief Instant Relief Sensitive Toothpaste - 75ml More Images Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. Can be used after the Colgate Sensitive Pro-Relief Desensitizing Paste. Colgate Professional has resources to help your patients understand what causes enamel erosion and how to avoid falling into those traps. A comparative clinical study investigating the efficacy of a dentifrice containing 8% strontium acetate and 1040 ppm fluoride in a silica base and a control dentifrice containing 1450 ppm fluoride in a silica base to provide immediate relief of dentin hypersensitivity. Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. Pro-Argin Technology with arginine and an insoluble calcium compound, zinc and 1450ppm fluoride. Read our disclaimer for details. Toothpaste doesn't only clean your teeth; we have products to help with a variety of tooth issues like sensitivity and more. For patients in the dental chair, it can be used to rapidly ease hypersensitivity pain, facilitate examinations and make dental procedures more comfortable. The datasets analysed during the current study are available from the corresponding author on reasonable request. 4.2 5 0 221 221 Colgate Sensitive Pro-Relief Enamel Rebuild toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. Colgate Sensitive Pro-Relief Multi Protection Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily 2012;12(3):2208. Colgate Sensitive Instant Relief Whitening Toothpaste 75 ml Pack of 5, Blocks Pain Instantly, Prevents Sensitivity, Gently Removes Stains (5 x 75 ml) 1,230 5 offers from 12.50 Colgate Sensitive Pro Relief Enamel Repair Toothpaste 75ml - 4 packs 94 22 offers from 14.14 Colgate Sensitive Instant Relief Enamel Repair Toothpaste 75 ml 190 The loss of tooth enamel is the most common cause of tooth sensitivity and is not affected by cavities, gum disease, or other problems. Yang ZY, Wang F, Lu K, Li YH, Zhou Z. Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis. Schulz KF, Altman DG, Moher D. CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. Helps protect teeth against cavities and promotes healthy gums (with regular brushing). The primary analysis population could be described as 32 participants per treatment group after lost to follow-ups of 12 out of 35 enrolled in the six-week trial who responded to the air blast stimulus for the primary outcome measure of treatment response one minute after topical application and after three days and two, four and six weeks subsequently, on SCASS with scores of2. Gently and effectively removes stains. Formulated with Pro-Argin technology, Colgate Sensitive Pro-Relief is clinically proven instant and lasting sensitivity relief*. J Clin Dent. Treatment difference between FCPS, Pro-argin, and 8% strontium acetate was not statistically significant with a p>0.05 for sustained pain relief in DH. *with direct application and daily brushing. No adverse events like gingival inflammation, bad taste, allergies, fluoride incompatibility, and dental or tongue stains were observed for all dentifrices. 2017;59(4):4618. These measures facilitated behaviour modification together with the promotion of knowledge and understanding in the society about DH. Colgate Sensitive Instant Relief Enamel Toothpaste with Pro-Argin technology to help seal and repair the sensitive areas of teeth. Children 6 years and younger: use a pea-sized amount for supervised tooth brushing to minimise swallowing. * with direct application and daily brushing Benefits Exclusive Pro-Argin formula Prevents sensitivty coming back 7 Ipsos, UK Patient Experience Programme on Colgate SENSITIVE PRO-Relief, results collected after 2 weeks trial, 192 respondents, 2016. However, we can conclude that both Pro-argin and strontium acetate-based dentifrices disrupt the pathophysiology of DH and are effective for immediate pain relief even one minute after application on sensitive teeth. However, the manufacturers of the tested dentifrices were acknowledged in the study [34], so information bias wasexpected in the conducted trial. Tandkrmen innehller zink fr att strka tandkttet och frhindra att tandkttet drar sig tillbaka, vilket r en av de vanligaste orsakerna till att . Buy Colgate Sensitive Pro Relief and get the best deals at the lowest prices on eBay! Dziki unikalnej formule Pro-Argin z arginin, wzmacnia szkliwo zbw i tym samym staj si one bardziej odporne na dziaanie kwasw. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste for the daily oral care of patients with dentine hypersensitivity and gum problems. 2020;99(5):51422. 0:00 / 0:30 Colgate Sensitive Pro-Relief Challenge Advert April 2012 178,990 views Mar 29, 2012 Take the Colgate Sensitive Pro-Relief Challenge to Show more 15 Dislike Share. Nathoo S, Delgado E, Zhang YP, DeVizio W, Cummins D, Mateo LR: Comparing the efficacy in providing instant relief of dentine hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a benchmark desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride and to a control toothpaste with 1450 ppm fluoride: A three-day clinical study in New Jersey, USA. 2009;20(1):106. Colgate Sensitive Pro Relief offers a solution that is clinically proven to relieve sensitivity pain. 2018. Oral dentifrices were provided to the subject free of cost. 2017;30(4):2216. *with direct application and daily brushing. Akber A, Ali NS, Shabbir S, Wahid U, Farooqui WA. Directions *For instant relief, apply directly to the sensitive tooth with fingertip, and massage gently for 60 seconds, one a week or less frequently **For lasting relief, apply to a gentle toothbrush making sure to brush all sensitive areas of the teeth. Pessoa OF, Loretto SC, Maia LC. IADR, The Excel, United Kingdom. Colgate Sensitive Instant Relief Toothpaste starts blocking sensitivity pain instantly*. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. J Clin Dent 20 (2009), special issue 17-22, 3. Table 5 presents the change in the mean scores of VAS against mechanical stimulus from baseline to subsequent efficacy interval within each treatment arm. Lg i kurv. 2 Docimo et al. This trial was registered in an ICMJE approved registry at https://clinicaltrials.gov/) under protocol Identifier: NCT04249336 [19] following the CONSORT guidelines [20] for parallel-group randomized trials after approval from the Institutional Review Board of Dow University of Health Sciences with reference no. Therefore, this trial was planned to investigate the clinical efficacy of Pro-argin and strontium acetate for immediate pain relief in DH after one minute of topical application to fill the research gap associated with limited published evidence and risk of bias in selection, performance, attrition, and reporting as predicted by Pessoa et al. Dentin hypersensitivity can have significant detrimental effects on your patients wellbeing and quality of life. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). A toothbrushing demonstration model from Nissin Company specification [PE-ORT002] was used to explain to the study participants about applying OTC dentifrices for one minute with the participant's finger. 2017;457:2530. Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 Martins CC, Firmino RT, Riva JJ, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. Clinically proven lasting relief for 8 weeks. Dentine hypersensitivity (DH) is a chronic condition with acute, transient pain in non-carious teeth that originates in response to thermal stimuli such as hot or cold, chemicals like acidic or sweet or salt, and mechanical stimuli due to exposure to dentinal tubules without any apparent clinical disease [1]. Clinically proven Instant and lasting Sensitivity relief*. 2. Yes, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste should be used for twice daily toothbrushing to provide ongoing relief from the pain of sensitive teeth.